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Active Ingredients
Active Ingredients
Active ingredients and high toxicity drugs – High performance sieving and filtration that safeguard your operators' health
The development and manufacture of Active Pharmaceutical Ingredients (API’s) and high toxicity drugs can be an extremely long and expensive process. It is absolutely necessary every piece of equipment used within each stage of this process is supplied with both the highest quality in mind and the best customer support available.
Easy clean equipment to help eliminate cross contamination of liquids and powders
Eliminating cross contamination when sieving or filtering API’s or high toxicity drugs is critically important. Russell Finex therefore ensure their equipment can be easily cleaned between batches. This is achieved by guaranteeing all product contact parts can easily be stripped down.
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Wet In Place and Clean in Place for powders
Cleaning down time can be minimized with the inclusion of the ‘Wet in Place’ spray ball system, designed to wet toxic powders before strip down. The ‘Clean in Place' is also designed to handle highly sensitive or intravenous drugs, providing total in line screening.
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Obtain optimum particle size distributions
As with most pharmaceutical applications, obtaining the correct particle size distribution of active ingredients is essential for a consistent, high quality drug. To achieve this Russell Finex uses only the highest quality sieve mesh in all sieves and separators.
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Dust-containment during sieving
Employers have been using occupational exposure limits (OEL’s) for many years to safeguard the health of their employees. Due to the nature of sieving, dust containment can often be a problem particularly where API’s or high toxicity drugs are involved. As a result of listening and working closely with our customers, Russell Finex have developed innovative ways to minimize the risks associated with product containment. We have been the first to develop a sieve able to meet OEL containment level 5, providing dust containment levels below 1µg/m3.
Full Documentation
Russell Finex can also help you achieve approval and validation of your process with a complete documentation package.
Read more
Learn more about Russell Finex and the active ingredients industry either by viewing our most recent stories in the related media section at the top of this page or by moving to our pharmaceutical case studies section.