Home News and Events Ensuring safe API handling with OEL 5 containment

Ensuring safe API handling with OEL 5 containment

October 27, 2025

Protect your operators with our advanced containment equipment for pharmaceutical screening

The use of high-potency active pharmaceutical ingredients (HPAPIs) has accelerated in recent years, driven by the growing demand for precise, targeted therapies to treat complex diseases. These compounds deliver strong therapeutic effects even at low doses, but with that potency comes risk. During handling or screening of API’s, even minimal dust exposure can pose serious health hazards to operators. Achieving the right level of containment in pharmaceutical powder handling is therefore crucial to meet regulatory requirements and protect lives.

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The challenge: Invisible risks in pharmaceutical powder handling

High potent API screening presents significant risk when containment systems struggle to deliver truly dust-tight performance. Factors such as gasket slippage, misalignment seals or inconsistent clamping validation can allow hazardous dust to escape into the environment. Traditional sieving equipment may also require complex disassembly and cleaning, increasing the likelihood of exposure during maintenance. To ensure operator safety, product integrity, and regulatory compliance, pharmaceutical manufacturers need equipment specifically designed for high containment and efficiency.

The Solution: Purpose-built all-in-one containment equipment

Designed for high-containment pharmaceutical screening, our Russell Compact Airlock Sieve™ offers a complete solution for safe and efficient powder processing. This enclosed vibratory screener protects operators, safeguards product quality, and ensures easy, tool-free operation while meeting strict cGMP standards. Its compact design is optimized for cleanroom environments and enables high-capacity screening with a minimal footprint.

Its patented Twist-Lock Inflate (TLI) airlock clamping system ensures validated OEL 5 containment performance. This unique design securely locks the sieve components in position and then the airlock inflates to create a uniform OEL level seal across all contact points preventing dust leakage. Tool-free operation and easy disassembly further reduces downtime and minimizes contamination risks, making it ideal for use at any stage of the pharmaceutical manufacturing process.

Proven success in real world application

The leading pharmaceutical manufacturer, Cipla Ltd required an OEL-compliant, dust-tight screening solution that guarantee both product quality and operator safety. After installing our Russell Compact Airlock Sieve™ at their new OEL-compliant facility, Cipla reported significant improvement to their existing working condition. They said “It is extremely easy to dismantle when compared to conventional clamping methods. It is clear that this particular unit has been designed specifically for this type of application.”

For over 90 years, we have been developing innovative separation and filtration equipment for the pharmaceutical industry. We continue to collaborate with our customers to develop solutions that meet their evolving production demand. Our machines are engineered to uphold the highest standards of product quality, process efficiency, and ease of maintenance, delivering reliable performance and helping you achieve your productivity goals in pharmaceutical applications.

Speak to our experts to discuss your pharmaceutical containment requirements.

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